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“We also found that while over time there was no effect of direct to consumer advertisement on tegaserod prescriptions, for every $243 spent promoting tegaserod to physicians one additional prescription was written. Tegaserod has not been adequately studied in patients with moderate to severe hepatic impairment, and its use is not recommended. Food and Drug Administration says it will allow restricted use of the irritable bowel syndrome drug Zelnorm (tegaserod maleate) among certain women younger than age 55. It is not known whether tegaserod passes into breast milk or if it could harm a nursing baby. Tegaserod is also used to treat women younger than 55 years of age who have chronic constipation with an unknown cause.

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